Glycosylation Analysis Service

28/05/2020

M-Scan's glycosylation analysis service is designed to encompass the requirements of the ICH guidelines. Our analytical services are available to GLP /cGMP together with advice from recognised M-Scan glycan experts. M-Scan's glycosylation analysis package includes the following:- Monosaccharide composition analysis of neutral and amino sugars by GC-MS- Sialic Acid Analysis by HPAEC-PAD to assess levels of sialic acid species such as NeuAc and NeuGc- Glycosyalion site analysis to assess the population profile of the N-glycans or O-glycans present at each glycosylation site in a glycoprotein- Oligosaccharide population analysis by MALDI-TOF to assess the overall population profile of the N-glycans or O-glycans present in a glycoprotein.- Glycan antennary profiling analysis by ESI-MS.- Linkage (methylation) analysis to determine the identities of the various linkages between the monosaccharides present in a glycoprotein.The glycosylation analysis service can be tailored to our clients' requirement - individual analyses, or a full glycosylation analysis package can be performed to GLP or GMP.