Most topical treatments do not have much effect, due to the nail being a drug barrier, therefore nothing can get underneath the nail. Clearanail allows access for the topical treatment recommended to reach the infection. My opinion: Clearanail - "The best fungal nail treatment that i have worked with for 20 years is finally available to my clients. Most clients looking for a clear nail are desperate to eradicate this nail condition & usually have had the problem for years and will try anything to get rid of their fungal nail. I'm so excited and proud to offer this revolutionary treatment to patients and seeing clear photographic evidence that this really works. Its truly a significant breakthrough in technology.